Preview: Cardinals vs. Broncos · prediction, injury report, analysis
The Arizona Cardinals (2-4) host the Denver Broncos (4-2) in Week 7 of the NFL season. Kickoff is on Sunday, October 25 at 4:05 p.m. ET at State Farm Stadium in Glendale.
Arizona sits third in the NFC West. Denver is second in the AFC West.
Match preview
Arizona is 2-4 after an 18-16 win over the Rams in Week 6. It was the Cardinals' first victory after four straight losses: 31-7 to Seattle, 36-30 to San Francisco, 36-24 to the Giants and 45-21 to Detroit.
The offense averages 21.0 points per game (126 in six outings). The defense allows 29.7 per game (178 in total).
The Cardinals have not won at home. They are 0-2 at State Farm Stadium and carry a nine-game home losing streak, according to ProFootball Talk. They have also lost 17 straight against teams with winning records, per FOX Sports.
Rookie running back Jeremiyah Love, the No. 3 overall pick in the 2026 draft, leads the offense with 245 rushing yards and a touchdown in five games, at 3.7 yards per carry. Against the Rams, Tyler Allgeier had 18 carries and Bam Knight added 15 for 80 yards.
Denver arrives at 4-2 on a two-game winning streak: 23-17 over the Chargers and 17-14 over Seattle. Its most recent loss was 24-14 at San Francisco in Week 4. Before that, the Broncos beat the Rams 30-26 and Jacksonville 20-13.
The Broncos' offense averages 19.0 points per game (114 in six). The defense gives up 20.8 (125), the 10th-best mark in the league, according to CBS Sports.
Quarterback Bo Nix has 1,049 passing yards, six touchdowns and three interceptions. His 5.6 yards per attempt is the lowest among quarterbacks who have started every game for their teams.
Denver is 3-0 at home and 1-2 on the road. Its run defense ranks 31st in the NFL, allowing 139.8 yards per game.
The recent history favors Denver. The Broncos won the last regular-season meeting 24-15 on December 18, 2022. They also won preseason games 27-7 in 2025 and 38-12 in 2024, while Arizona took a 18-17 decision in 2023.
Arizona Cardinals · recent results
- WLos Angeles Rams 16-18 Arizona Cardinals
- LArizona Cardinals 21-45 Detroit Lions
- LNew York Giants 36-24 Arizona Cardinals
- LSan Francisco 49ers 36-30 Arizona Cardinals
- LArizona Cardinals 7-31 Seattle Seahawks
Denver Broncos · recent results
- WDenver Broncos 17-14 Seattle Seahawks
- WLos Angeles Chargers 17-23 Denver Broncos
- LSan Francisco 49ers 24-14 Denver Broncos
- WDenver Broncos 30-26 Los Angeles Rams
- WDenver Broncos 20-13 Jacksonville Jaguars
Key stats
Trends · last 5 matches
Injury report
Arizona has ruled out running back Jeremiyah Love (ankle), defensive tackle Walter Nolen III (ankle), guard Jon Gaines II and Wingard (knee). Hayden Conner will step in at right guard.
The Cardinals list four players as questionable: safety Budda Baker (groin and illness), cornerback Max Melton (knee), Darius Robinson (back) and rookie quarterback Carson Beck (back), the team's third quarterback.
Denver ruled out running back Tyler Badie (thumb), outside linebacker Jonah Elliss (ankle) and safety Talanoa Hufanga (ankle). Cornerback Pat Surtain II (ankle) has not played since Week 4 and is questionable. So is running back Jonah Coleman (ankle), who needs to be activated from injured reserve.
Wide receiver Jaylen Waddle (chest) and cornerback Riley Moss (ribs) were full participants on Friday and carry no game designation.
We expect Denver to win 20-13. Arizona is short-handed in the trenches and without Love, and its defense is allowing nearly 30 points per game. Nix and the Broncos' offense have limits, but their defense should keep the game tight, and a couple of sustained drives plus field goals should be enough.